There are various health risks throughout the African continent that may end your trip on a tragic note.
In order to enter most African countries you will need to have a valid vaccination certificate showing that you were vaccinated against yellow fever and cholera.
Get vaccinated at least 3 weeks before your trip against yellow fever, cholera, tetanus, typhoid, polio, tuberculosis, and meningitis.
Malaria is endemic throughout East Africa and you need to take a prophilactics such as Larium, Malarone or Doxypalu.
Check with your local doctor, as in certain areas the malaria parasite has acquired immunity to some of the drugs. Note that drugs are not 100% effective, avoiding to get bitten by mosquitoes is so the best way to protect yourself.
Cook it, boil it, peel it or leave it: don't drink tap water, this includes ice in drinks, and raw foods.
Avoid sex as there